4-test-Octylphenol: Technical Analysis of a Multifunctional Chemical Raw Material

 4-tert-octylphenol, also known as p-tert-octylphenol (POP), is a chemical raw material with wide industrial application value.

CAS No.: 140-66-9,
Molecular formula: C14H22O

Specification:

ITEM OF ANALYSIS	SPECIFICATION
APPEARANCE	WHITE POWDER
ASSAY(%)	99
FLASH POINT (ºC)	145
DENSITY G/CM3 (20 ºC)	0.95
BOILING POINT  ºC, 30MM HG (LTD.)	175
MELTING POINT ºC(LTD.)	79-82
SPECIFIC GRAVITY	1.038-1.051
REFRACTIVE INDEX ND (20ºC)	1.557-1.569
MOISTURE(%)	0.1 MAX

This information provides basic chemical references for researchers and producers when selecting and using this raw material.
4-test-Octylphenol appears as a white solid powder at room temperature and has good solubility. It can be dissolved in water and a variety of organic solvents. This chemical property makes it highly flexible in chemical production and easy to use under different reaction conditions.

In the chemical industry, 4-tert-octylphenol is widely used in the manufacture of oil-soluble phenolic resins, surfactants, adhesives, and other products. Oil-soluble phenolic resins are important raw materials in the fields of coatings, plastics, rubber, etc., while surfactants play an important role in detergents, cosmetics, and other products. In addition, 4-tert-octylphenol is also used to make medicines, pesticides, additives, ink fixatives, etc., demonstrating its versatility and wide industry applicability.

However, 4-tert-octylphenol not only has industrial application value but also has biological activity. Studies have shown that it is an endocrine disruptor with estrogenic activity that can affect the endocrine system of organisms. In studies on mice, 4-tert-octylphenol was found to induce apoptosis of progenitor cells in the brain neurons of offspring mice and affect the brain development and behavior of mice. This discovery makes 4-tert-octylphenol potentially valuable in research in the fields of neuroscience, immunology, and behavior.

From the perspective of production and preparation, the synthesis process of 4-tert-octylphenol is also challenging. A common synthesis method is to react 4-tert-octylphenol with alkyl iodide under alkaline conditions to form the corresponding alkyl ether derivatives by nucleophilic substitution. This process requires strict reaction conditions, such as an anhydrous environment and argon protection, to ensure the efficiency and safety of the reaction.

During the application process, attention should be paid to the potential environmental risks of 4-tert-octylphenol. Due to its endocrine-disrupting effect, long-term exposure or large-scale discharge may have adverse effects on the environmental ecosystem. Therefore, during production and use, discharge should be strictly controlled and appropriate treatment measures should be taken to reduce its impact on the environment.

As a multifunctional chemical raw material, 4-tert-octylphenol has broad application prospects in the chemical industry. At the same time, its biological activity and environmental effects also provide us with new research directions and application fields. In the future, with the continuous deepening of scientific research and the continuous advancement of technology, it is believed that 4-tert-octylphenol will play its unique role in more fields.